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Seminar: Kimberly Sellers

Statistics Seminar
January 6, 2004
All Day
209 W. Eighteenth Ave. (EA), Room 170

Title

Accounting for Systematic Variation in Difference Gel Electrophoresis

Speaker

Kimberly Sellers, Carnegie Mellon University

Abstract

Two-dimensional Difference Gel Electrophoresis (DIGE) circumvents many of the problems associated with gel comparison via the traditional approach, two-dimensional gel electrophoresis (2DE). DIGE's accuracy, however, can be further improved by removing the many associated sources of systematic variation. In this talk, I will identify these sources (including those caused by the apparatus detection system for locating proteins) and illustrate the results using data from a collection of experiments.