Title
On Assessing Agreement in Method Comparison Studies
Speaker
Pankaj Choudhary, The Ohio State University
Abstract
This talk will focus on two issues in method comparison studies. First, if there is "sufficient" agreement between two competing instruments, the less expensive or the easier-to-use instrument is preferable. The statistical problem here is to assess the degree of agreement. An overview of the existing practices will be presented, followed by three new approaches for testing the hypotheses of satisfactory agreement. The appropriate approach to use is guided by goals of the experiment and the experimenter's ability to specify the thresholds. The advantages of the new approaches over the existing ones will be illustrated using a dataset from medical literature. Second, if two instruments are compared with a gold-standard, it is desirable to select the instrument that agrees most with the gold-standard. A large sample two-stage indifference zone procedure will be presented for this selection problem. Questions like which parameterization is the "best" and what first-stage sample size is "adequate" are answered using simulation. This technique will also be illustrated using a dataset from literature.
This is joint work with my advisor professor H. N. Nagaraja.
Meet the speaker in Room 212 Cockins Hall at 4:30 p.m. Refreshments will be served.
